Product Description
Recombinant Human Synaptosomal-associated protein 25 (SNAP25) is available at Gentaur for Next week Delivery.
Gene Name: SNAP25
Alternative Names : Super protein;SUPSynaptosomal-associated 25KDA protein
Expression Region : 1-206aa
AA Sequence : MAEDADMRNELEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDRVEEGMNHINQDMKEAEKNLKDLGKCCGLFICPCNKLKSSDAYKKAWGNNQDGVVASQPARVVDEREQMAISGGFIRRVTNDARENEMDENLEQVSGIIGNLRHMALDMGNEIDTQNRQIDRIMEKADSNKTRIDEANQRATKMLGSG
Sequence Info : Full Length of Isoform 2
Tag Info : N-terminal 6xHis-tagged
Theoretical MW : 27.3 kDa
Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level : Not tested-
Biological Activity : Not tested
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Neuroscience
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systs. Associates with proteins involved in vesicle docking and mbrane fusion. Regulates plasma mbrane recycling through its interaction with CENPF.
Function : t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells.
Involvement in disease : Myasthenic syndrome, congenital, 18 (CMS18)
Subcellular location : Cytoplasm, perinuclear region, Cell membrane, Lipid-anchor, Cell junction, synapse, synaptosome
Protein Families : SNAP-25 family
Tissue Specificity : Neurons of the neocortex, hippocampus, piriform cortex, anterior thalamic nuclei, pontine nuclei, and granule cells of the cerebellum.
Paythway : Excitatorysynapsepathway
Uniprot ID : P60880