Recombinant Human Thymosin beta-4 protein (TMSB4X) (Active)

Product Description

Recombinant Human Thymosin beta-4 protein (TMSB4X) (Active) is available at Gentaur for Next week Delivery.

Gene Name: TMSB4X,TB4X,THYB4,TMSB4

Alternative Names : T beta-4,

Expression Region : 2-44aa

AA Sequence : SDKPDMAEIE KFDKSKLKKT ETQEKNPLPS KETIEQEKQA GES

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 4.9 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The biological activity determined by its ability to produce a protective effect against hydrogen peroxide in primary lung fibroblasts is in a concentration range of 0.5 - 10 ?g/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. {ECO:0000250}.; Seraspenide inhibits the entry of hematopoietic pluripotent stem cells into the S-phase. {ECO:0000250}.

Function : Plays an important role in the organization of the cytoskeleton (By similarity). Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization.

Involvement in disease :

Subcellular location : Cytoplasm, cytoskeleton

Protein Families : Thymosin beta family

Tissue Specificity : Expressed in several hemopoietic cell lines and lymphoid malignant cells. Decreased levels in myeloma cells.

Paythway : Regulationofactincytoskeleton

Uniprot ID : P62328