Recombinant Human VEGF coregulated chemokine 1 protein (CXCL17) (Active)

Product Description

Recombinant Human VEGF coregulated chemokine 1 protein (CXCL17) (Active) is available at Gentaur for Next week Delivery.

Gene Name: CXCL17,VCC1,UNQ473/PRO842

Alternative Names : C-X-C motif chemokine 17, DMC

Expression Region : 22-119aa

AA Sequence : SSLNPGVARG HRDRGQASRR WLQEGGQECE CKDWFLRAPR RKFMTVSGLP KKQCPCDHFK GNVKKTRHQR HHRKPNKHSR ACQQFLKQCQ LRSFALPL

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 11.5 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by its ability to induce VEGF expression using murine endothelial cells is less than 5.0 ?g/ml, corresponding to a specific activity of ? 200 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Plays a role in angiogenesis and possibly in the development of tumors. May be a housekeeping chemokine regulating recruitment of nonactivated blood monocytes and immature dendritic cells into tissues. May play a role in the innate defense against infections. {ECO:0000269|PubMed:16455961, ECO:0000269|PubMed:16989774, ECO:0000269|PubMed:17307946}.

Function : Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells

Involvement in disease :

Subcellular location : Secreted

Protein Families : Intercrine alpha (chemokine CxC) family

Tissue Specificity : Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation.

Paythway :

Uniprot ID : Q6UXB2