Product Description
Recombinant Mouse Beta-defensin 1 (Defb1) is available at Gentaur for Next week Delivery.
Gene Name: Defb1
Alternative Names : Short name:BD-1 Short name:mBD-1
Expression Region : 33-69aa
AA Sequence : DQYKCLQHGGFCLRSSCPSNTKLQGTCKPDKPNCCKS
Sequence Info : Full Length of Mature Protein
Tag Info : N-terminal 6xHis-SUMO-tagged
Theoretical MW : 20.1 kDa
Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level : Not tested-
Biological Activity : Not tested
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Others
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Has bactericidal activity.
Function : Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
Involvement in disease :
Subcellular location : Secreted, Membrane
Protein Families : Beta-defensin family
Tissue Specificity : Detected in kidney.
Paythway :
Uniprot ID : P56386