Recombinant Mouse C-C motif chemokine 27 protein (Ccl27) (Active)

Product Description

Recombinant Mouse C-C motif chemokine 27 protein (Ccl27) (Active) is available at Gentaur for Next week Delivery.

Gene Name: Ccl27,Ilc,Scya27

Alternative Names : CC chemokine ILC, CTACK, ESkine, IL-11 R-alpha-locus chemokine, ALP

Expression Region : 26-120aa

AA Sequence : LPLPSSTSCC TQLYRQPLPS RLLRRIVHME LQEADGDCHL QAVVLHLARR SVCVHPQNRS LARWLERQGK RLQGTVPSLN LVLQKKMYSN PQQQN

Sequence Info : Partial of NM_011336

Tag Info : Tag-Free

Theoretical MW : 10.9 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The biological activity determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 10-100 ng/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10.

Function : Chemotactic factor that attracts skin-associated memory T-lymphocytes. May play a role in mediating homing of lymphocytes to cutaneous sites. May play a role in cell migration during embryogenesis. Nuclear forms may facilitate cellular migration by inducing cytoskeletal relaxation. Binds to CCR10.

Involvement in disease :

Subcellular location : Isoform 1: Secreted, Nucleus

Protein Families : Intercrine beta (chemokine CC) family

Tissue Specificity : Isoform 1 is predominantly expressed in placenta and weakly in skin. Isoform 2 is predominantly expressed in testes and brain, weakly in kidney and liver and even lower in heart and muscle. Low expression of both isoforms in other tissues.

Paythway :

Uniprot ID : Q9Z1X0