Product Description
Recombinant Mouse C-C motif chemokine 3 protein (Ccl3) (Active) is available at Gentaur for Next week Delivery.
Gene Name: Ccl3,Mip1a,Scya3
Alternative Names : Heparin-binding chemotaxis protein, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, SIS-alpha, Small-inducible cytokine A3
Expression Region : 24-92aa
AA Sequence : APYGADTPTA CCFSYSRKIP RQFIVDYFET SSLCSQPGVI FLTKRNRQIC ADSKETWVQE YITDLELNA
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 7.9 kDa
Storage Buffer : Lyophilized from a 0.2 ?m filtered concentrated solution in 30 % Acetonitrile and 0.1 % TFA
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The biological activity determined by a chemoattract bioassay using murine splenocytes is in a concentration range of 10-100 ng/ml.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Immunology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.
Function : Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Intercrine beta (chemokine CC) family
Tissue Specificity : Expressed in lung, spleen, and pancreas.
Paythway :
Uniprot ID : P10855