Product Description
Recombinant Poecilobdella viridis protein (HIRUD) (Active) is available at Gentaur for Next week Delivery.
Gene Name: N/A
Alternative Names :
Expression Region : 1-63aa
AA Sequence : VVYTDCTESG QNLCLCEGSN VCGQGNKCIL GSDGEKNQCV TGEGTPGPQS HNDGDFEEPE EYL
Sequence Info : Full Length
Tag Info : Tag-Free
Theoretical MW : 6.7 kDa
Storage Buffer : Lyophilized from a 0.2 ?m filtered 20 mM PBS, pH 7.0, containing 2 % mannitol
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The biological activity is determined by chromogenic assay, 1 unit is defined as the amount of Hirudin that neutralizes 1 unit of the WHO preparation 89/588 of thrombin. The specific activity is no less than 14,000 ATU/mg protein.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Neuroscience
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.
Function : Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Protease inhibitor I14 (hirudin) family
Tissue Specificity :
Paythway :
Uniprot ID : P84590