Product Description
Recombinant Rhesus Macaque Interferon gamma protein (IFNG) (Active) is available at Gentaur for Next week Delivery.
Gene Name: IFNG
Alternative Names : IFN-gamma,
Expression Region : 24-165aa
AA Sequence : QDPYVKEAEN LKKYFNAGDP DVADNGTLFL DILRNWKEES DRKIMQSQIV SFYFKLFKNF KDDQRIQKSV ETIKEDINVK FFNSNKKKRD DFEKLTNYSV TDSNVQRKAV HELIQVMAEL SPAAKIGKRK RSQMFRGRRA SQ
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 16.8 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The ED50 as determined by an anti-viral assay using human HeLa cells infected with encephalomyocarditis (EMC) virus is less than 20.0 ng/ml, corresponding to a specific activity of ? 5.0 ×104 IU/mg.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Immunology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Function : Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Involvement in disease :
Subcellular location : Secreted
Protein Families : Type II (or gamma) interferon family
Tissue Specificity : Released primarily from activated T lymphocytes.
Paythway :
Uniprot ID : P63310