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Monoclonal Antibody

Signal transduction pathways engaged downstream of B cell receptor (BCR) signaling

Vomparison to analogous pathways engaged downstream of the T cell receptor (TCR). It also covers the 2 main categories of antigens that can activate B cells, and the effects that these have on either IgM antibody responses that provide immediate protection or germinal center responses that provide higher quality antibodies through the processes of affinity maturation and class switching.