Gamma Synuclein Protein is available at Gentaur for Next week delivery.
Description: Active Mouse Recombinant Gamma Synuclein Protein Preformed Fibrils (Type 1)
Alternative Name(s): BCSG1 Aggregate Protein, Breast cancer specific gene 1 Aggregate Protein, Breast cancer specific Protein 1, Gamma-synuclein Aggregate Protein, Persyn Aggregate Protein, PRSN Aggregate Protein, SNCG Aggregate Protein, SR Aggregate Protein, Synoretin Aggregate Protein, Synuclein gamma Aggregate Protein, SYUG_HUMAN Aggregate Protein
Research Area(s): Neuroscience | Neurodegeneration | Alzheimer's Disease | Tangles & Tau | Neuroscience | Neurodegeneration | Parkinson's Disease | Synuclein
Accession Number: NP_035560.1
Gene ID: 20618
Applications Species: WB | SDS-PAGE | In vivo assay | In vitro assay
Expression System: E. coli
Protein Length: Full length
Amino Acid Sequence:
Purification: Ion-exchange Purified
Storage Buffer: PBS pH 7.4
Concentration: Lot/batch specific. See included datasheet.
Shipping Temperature: Dry Ice. Shipping note: Product will be shipped separately from other products purchased in the same order.
Other relevant information: For best results, sonicate immediately prior to use. Refer to the Neurodegenerative Protein Handling Instructions on our website, or on the product datasheet for further information..
Certificate of Analysis: Certified >95% pure using SDS-PAGE analysis.
Cellular Localization: Cytoskeleton | Centrosome | Spindle | Perinuclear Region
Scientific Background: Gamma synuclein is a neuronal protein found in peripheral and motor nerve systems. It has been implicated in the hippocampal axon pathology in Parkinson's Disease (1). A change in the expression of gamma synuclein has been observed in the retina of patients with Alzheimer's disease (2). Its expression in breast tumors is also a marker for tumor progression (3).
References: 1. Nishioka K., et al. (2010) Arch Neurol. 67(8): 970-975. 2. Surgucheva I., Newell K.L., Burns J., Surguchov A. (2014) Acta Neuropathol Commun. 2: 132. 3. Bruening. W., et al. (2000) Cancer. 88(9): 2154-2163. 4. Mukaetova-Ladinska E.B., et al. (2008) Dement Geriatr Cogn Disord. 26(1): 32-42.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For research use only.
Published Species Reactivity:"