Recombinant Paraponera clavata Poneratoxin

Product Description

Recombinant Paraponera clavata Poneratoxin is available at Gentaur for Next week Delivery.

Gene Name: N/A

Alternative Names : Pac-TX

Expression Region : 1-25aa

AA Sequence : FLPLLILGSLLMTPPVIQAIHDAQR

Sequence Info : Full Length

Tag Info : N-terminal 6xHis-tagged

Theoretical MW : 3.7 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Others

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Blocks nicotinic synaptic transmission in insect CNS and affects voltage-gated sodium channels (Nav). It is a strong, but very slowly acting agonist for smooth muscles and its blocks synaptic transmission in the insect CNS in a concentration-dependent manner and depolarizes giant interneurons. Also affects neuromuscular transmission in rat tissue.

Function : Blocks nicotinic synaptic transmission in insect CNS and affects voltage-gated sodium channels (Nav). It is a strong, but very slowly acting agonist for smooth muscles and its blocks synaptic transmission in the insect CNS in a concentration-dependent manner and depolarizes giant interneurons. Also affects neuromuscular transmission in rat tissue.

Involvement in disease :

Subcellular location : Secreted

Protein Families :

Tissue Specificity : Expressed by the venom gland.

Paythway :

Uniprot ID : P41736